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Research publications

Scientific papers about our projects :

Research publications

【The 14th Annual meeting of Asian Cellular Therapy Organization】

Comparative analysis of islets derived from patients with type 2 diabetes and healthy individuals using clinically optimized multi-omics analysis will be enhanced by information obtained from induced pluripotent stem cell (iPSC) generation techniques and

Yoshiki N , Tsukahara M

Yoshiki Nakashima, a research scientist at the CiRA Foundation, was selected as one of the 5 Excellent Abstracts and received the Investigators Awards at the conference.

Research publications

A clinical-grade HLA haplobank of human induced pluripotent stem cells matching approximately 40% of the Japanese population

Yoshida S , Kato TM , Sato Y , Umekage M , Ichisaka T , Tsukahara M , Takasu N , Yamanaka S

Med : doi.org/10.1016/j.medj.2022.10.003

Research publications

Improved Sendai viral system for reprogramming to naive pluripotency

Kunitomi A , Hirohata R , Arreola V , Osawa M ,Kato T , Nomura M , Kawaguchi J , Hara H , Kusano K , Takashima Y , Takahashi K , Fukuda K , Takasu N , Yamanaka S

Cell Reports Methods : doi.org/10.1016/j.crmeth.2022.100317

Research publications

Induced hepatic stem cells are suitable for human hepatocyte production

Nakashima Y , Miyagi-Shiohira C , Saitoh I , Watanabe M , Matsushita M , Tsukahara M , Noguchi H

iScience:doi.org/10.1016/j.isci.2022.105052

Research publications

Semi-3D cultures using Laminin 221 as a coating material for human induced pluripotent stem cells

Nakashima Y , Yoshida S , Tsukahara M

Regenerative Biomaterials : doi.org/10.1093/rb/rbac060

Research publications

Adhesion Characteristics of Human Pancreatic Islets, Duct Epithelial Cells, and Acinar Cells to a Polymer Scaffold

Nakashima Y , Iguchi H, Takakura K , Nakamura Y , Izumi K , Koba N , Haneda S , Tsukahara M

Cell Transplantation : doi.org/10.1177/09636897221120500

Research publications

Laminin-511 Activates the Human Induced Pluripotent Stem Cell Survival via α6β1 Integrin-Fyn-RhoA-ROCK Signaling

Nakashima Y , Tsukahara M

Stem Cells and Development : doi.org/10.1089/scd.2022.0010

Research publications

Generation of hypoimmunogenic induced pluripotent stem cells by CRISPR-Cas9 system and detailed evaluation for clinical application

Kitano Y, Nishimura S, Kato T, Ueda A, Takigawa K, Umekage M, Nomura M, Kawakami A, Ogawa H, Huaigeng X , Hotta A , Takasu N, Tsukahara M*

Molecular Therapy - Methods & Clinical Development : doi.org/10.1016/j.omtm.2022.05.010

Research publications

A chemically-defined plastic scaffold for the xeno-free production of human pluripotent stem cells

A chemically-defined plastic scaffold for the xeno-free production of human pluripotent stem cells

Shimizu E, Iguchi H, Le M N T, Nakamura Y, Kobayashi D, Arai Y, Takakura K, Benno S, Yoshida N, Tsukahara M, Haneda S, Hasegawa K

Scientific Reports volume 12: 2516 doi.org/10.1038/s41598-022-06356-8 (2022)

Research publications

Grafting of iPS cell-derived tenocytes promotes motor function recovery after Achilles tendon rupture

Nakajima T, Nakahata A, Yamada N, Yoshizawa K, Kato TM, Iwasaki M, Zhao C, Kuroki H, Ikeya M

Nature Communications 12: 5012 doi: 10.1038/s41467-021-25328-6

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